Research Interests
· Nanoscale-based targeted delivery of drugs, peptides, siRNA and antisense oligonucleotides in order to enhance the efficiency of treatment and imaging.
· Nanoparticle formulation, characterization and testing.
· Preclinical in vitro and in vivo evaluation of anticancer therapeutics.
· Orthotopic and ectopic animal models of cancer, lung diseases and fibrosis.
· Personalized medicine.
· Hypoxia.
· Mechanisms of multidrug resistance and their suppression.
· Intracellular fate and molecular mechanisms of action of drugs.
· Pharmacokinetics and pharmacodynamics.